• Product NamePIK-294
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityPIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3Kα/β/γ, respectively.
• Target NamePI3K inhibitor
• CAS No. 900185-02-6
• Calculated MW 489.53
• Formulation C28H23N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=CC=CC=C1N1C(CN2N=C(C3=C2N=CN=C3N)C2=CC(O)=CC=C2)=NC2=CC=CC(C)=C2C1=O
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:p110α; p110α; p110β; p110γ; p110δ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 98 mg/mL (200.19 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Knight ZA, et al. Cell. 2006, 125(4), 733-747.2. Bobrovnikova-Marjon E, et al. Mol Cell Biol. 2012, 32(12), 2268-2278.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting