• Product NameSB202190 (FHPI)
• Brief DescriptionInhibitors
• Purification99.73%
• Biological ActivitySB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo.
• Target Namep38 MAPK inhibitor
• CAS No. 152121-30-7
• Calculated MW 331.34
• Formulation C20H14N3OF
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:FC1=CC=C(C=C1)C1=C(NC(N1)=C1C=CC(=O)C=C1)C1=CC=NC=C1
  Pathways:MAPK
  Receptor:p38α; p38β
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 12 mg/mL (36.21 mM); DMSO: 66 mg/mL (199.19 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Davies SP, et al. Biochem J, 2000, 351(Pt 1), 95-105.2. Nemoto S, et al. J Biol Chem, 1998, 273(26), 16415-16420.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting