• Product NameCNX-774
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCNX-774 is an irreversible, orally active, and highly selective BTK inhibitor with IC50 of <1 nM.
• Target NameBTK inhibitor
• CAS No. 1202759-32-7
• Calculated MW 499.5
• Formulation C26H22FN7O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CNC(=O)C1=NC=CC(OC2=CC=C(NC3=NC=C(F)C(NC4=CC(NC(=O)C=C)=CC=C4)=N3)C=C2)=C1
  Pathways:Angiogenesis
  Receptor:BTK
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL (4.0 mM); DMSO: 100 mg/mL (200.2 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Labenski M. 17th North Am Meet Int Soc Study Xenobiot (ISSX) 2011. Abst. P211.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting