• Product NameSP2509
• Brief DescriptionInhibitors
• Purification99.53%
• Biological ActivitySP2509 is a selective histone demethylase LSD1 inhibitor with IC50 of 13?nM, showing no activity against MAO-A, MAO-B, lactate dehydrogenase and glucose oxidase.
• Target NameHistone Demethylase inhibitor
• CAS No. 1423715-09-6
• Calculated MW 437.9
• Formulation C19H20ClN3O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C/C(=C/1\C=C(C=CC1=O)Cl)/NNC(=O)C2=CC(=CC=C2)S(=O)(=O)N3CCOCC3
  Pathways:Chromatin/Epigenetic
  Receptor:LSD1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 38 mg/mL (86.77 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fiskus W, et al. Leukemia. 2014, 28(11), 2155-2164.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting