• Product NameHS-173
• Brief DescriptionInhibitors
• Purification99.33%
• Biological ActivityHS-173 is a potent inhibitor of PI3Kα with IC50 value of 0.8 nM.
• Target NamePI3K inhibitor
• CAS No. 1276110-06-5
• Calculated MW 422.46
• Formulation C21H18N4O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC(=O)C1=CN=C2C=CC(=CN12)C1=CC(NS(=O)(=O)C2=CC=CC=C2)=CN=C1
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:PI3Kα
  Boling pt:
  Melting pt:
  Solubility:DMSO: 84 mg/mL warmed (198.83 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yun SM, et al. Y Lett. 2013 May 1;331(2):250-61.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting