• Product NameGanetespib (STA-9090)
• Brief DescriptionInhibitors
• Purification99.27%
• Biological ActivityGanetespib(STA-9090) is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells.
• Target NameHSP inhibitor
• CAS No. 888216-25-9
• Calculated MW 364.4
• Formulation C20H20N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C)C1=C/C(=C\2/NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)/C(=O)C=C1O
  Pathways:Cytoskeletal Signaling; Metabolism
  Receptor:HSP90
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40 mg/mL (109.76 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang Y, et al. Curr Opin Investig Drugs. 2010 Dec;11(12):1466-76. 2. Proia DA, et al. PLoS One. 2011 Apr 14;6(4):e18552.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting