• Product NameMPI-0479605
• Brief DescriptionInhibitors
• Purification99.23%
• Biological ActivityMPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases
• Target NameKinesin inhibitor
• CAS No. 1246529-32-7
• Calculated MW 407.51
• Formulation C22H29N7O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=C(NC2=NC3=C(NC=N3)C(NC3CCCCC3)=N2)C=CC(=C1)N1CCOCC1
  Pathways:Cytoskeletal Signaling
  Receptor:Mps1
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL warmed (4.9 mM); DMSO: 62 mg/mL warmed (152.14 mM)
  Appearance:Silver Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Tardif K D. et al. Molecular Y therapeutics, 2011, 10(12): 2267-2275.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting