• Product NameGSK-LSD1 dihydrochloride
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityGSK-LSD1 2hydrochloride is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B).
• Target NameHistone Demethylase inhibitor
• CAS No. 1431368-48-7
• Calculated MW 289.24
• Formulation C14H22Cl2N2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:Cl.Cl.C1C(NC2CCNCC2)C1C1=CC=CC=C1
  Pathways:Chromatin/Epigenetic
  Receptor:LSD1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Off-white Color Crystal Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Structural Genomics Consortium.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting