• Product NameMK3102
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityOmarigliptin(MK-3102) is a potent, selective and long-acting DPP-4 inhibitor with IC50 of 1.6 nM; highly selective over all proteases tested (IC50 > 67 _mu_M).
• Target NameDPP-4 inhibitor
• CAS No. 1226781-44-7
• Calculated MW 398.43
• Formulation C17H20F2N4O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CS(=O)(=O)N1C=C2CN(CC2=N1)[C@@H]3C[C@@H]([C@H](OC3)C4=C(C=CC(=C4)F)F)N
  Pathways:Proteases/Proteasome
  Receptor:DPP-4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Biftu T, et al. J Med Chem. 2014 Apr 24;57(8):3205-12.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting