• Product NameFimasartan(BR-A-657)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityFimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure.
• Target NameRAAS antagonist
• CAS No. 247257-48-3
• Calculated MW 501.65
• Formulation C27H31N7OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCCCC1=NC(C)=C(CC(=S)N(C)C)C(=O)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
  Pathways:Endocrinology/Hormones
  Receptor:AGTR1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Faint Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ryu S, et al. Biol Pharm Bull. 2013;36(3):467-74.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting