• Product NameElvitegravir(GS-9137, JTK-303)
• Brief DescriptionInhibitors
• Purification99.57%
• Biological ActivityElvitegravir (GS-9137, JTK-303) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.
• Target NameHIV Protease inhibitor
• CAS No. 697761-98-1
• Calculated MW 447.88
• Formulation C23H23ClFNO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)[C@@H](CO)N1C=C(C(=O)C2=CC(=C(C=C21)OC)CC3=C(C(=CC=C3)Cl)F)C(=O)O
  Pathways:Microbiology&virology; Proteases/Proteasome
  Receptor:HIV-1 IIIB; HIV-2 EHO; HIV-2 ROD
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 35 mg/mL (78.14 mM); DMSO: 90 mg/mL (200.94 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shimura K, et al. J Virol. 2008, 82(2), 764-774.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting