• Product NameJZL195
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityJZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.
• Target NameFAAH inhibitor; Lipase inhibitor
• CAS No. 1210004-12-8
• Calculated MW 433.46
• Formulation C24H23N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:[O-][N+](=O)C1=CC=C(OC(=O)N2CCN(CC3=CC(OC4=CC=CC=C4)=CC=C3)CC2)C=C1
  Pathways:Metabolism
  Receptor:FAAH; MAGL
  Boling pt:
  Melting pt:
  Solubility:DMSO: 50 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Long JZ, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20270-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting