• Product NameAS601245
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties.
• Target NameJNK inhibitor
• CAS No. 345987-15-7
• Calculated MW 372.45
• Formulation C20H16N6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:N#CC(C1=NC(NCCC2=CC=CN=C2)=NC=C1)C3=NC4=CC=CC=C4S3
  Pathways:MAPK
  Receptor:hJNK1; hJNK2; hJNK3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Carboni S, et al. Br J Pharmacol. 2008 Jan;153(1):157-163.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting