• Product NameEnasidenib
• Brief DescriptionInhibitors
• Purification99.45%
• Biological ActivityEnasidenib is a oral potent, selective, reversible inhibitor of mutant IDH2.
• Target NameDehydrogenase inhibitor
• CAS No. 1446502-11-9
• Calculated MW 473.38
• Formulation C19H17F6N7O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)(O)CNC1=NC(=NC(NC2=CC(=NC=C2)C(F)(F)F)=N1)C1=NC(=CC=C1)C(F)(F)F
  Pathways:Metabolism
  Receptor:IDH2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Stein EM, et al. ASH Annual Meeting. Abstract 115. Presented December 7, 2014.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting