• Product NameBRD7716
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity.
• Target NameDNA gyrase inhibitor
• CAS No. 329059-55-4
• Calculated MW 496.66
• Formulation C28H36N2O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1(C)C(C(=O)NC2=CC=C(C=C2)S(=O)(=O)C2=CC=C(NC(=O)C3C(C)(C)C3(C)C)C=C2)C1(C)C
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA gyrase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hartwell KA, et al. Nat Chem Biol. 2013 Dec;9(12):840-848

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting