• Product NameCFTRinh-172
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.
• Target NameCFTR inhibitor
• CAS No. 307510-92-5
• Calculated MW 409.4
• Formulation C18H10F3NO3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F
  Pathways:Membrane transporter/Ion channel
  Receptor:CFTR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 82 mg/mL (200.29 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ma T, et al. J Clin Invest. 2002, 110(11), 1651-1658.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting