• Product NameRo 3306
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityRO-3306 is an ATP-competitive, and selective CDK1 inhibitor with Ki of 20 nM, >15-fold selectivity against a diverse panel of human kinases.
• Target NameCDK inhibitor; ERK inhibitor; PKA inhibitor; PKC inhibitor; SGK inhibitor
• CAS No. 872573-93-8
• Calculated MW 351.45
• Formulation C18H13N3OS2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC2=C(C=CC(=C2)/C=C\3/C(=O)N=C(S3)NCC4=CC=CS4)N=C1
  Pathways:Cell Cycle/Checkpoint; Cytoskeletal Signaling; GPCR/G Protein; MAPK; Metabolism
  Receptor:CDK1; ERK; PKA; PKCδ; SGK
  Boling pt:
  Melting pt:
  Solubility:DMSO: 13 mg/mL warmed (36.98 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vassilev LT, et al. Proc Natl Acad Sci U S A. 2006, 103(28), 10660-10665.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting