• Product NameANA-12
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
• Target NameTrk receptor antagonist
• CAS No. 219766-25-3
• Calculated MW 407.49
• Formulation C22H21N3O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O=C(NC1=CC=CC=C1C(=O)NC1CCCCNC1=O)C1=CC2=CC=CC=C2S1
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:TrkB
  Boling pt:
  Melting pt:
  Solubility:DMSO: 37 mg/mL warmed (90.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cazorla M, et al. J Clin Invest. 2011, 121(5), 1846-1857.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting