• Product NameTipiracil hydrochloride
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityTipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an antiY drug candidate currently in clinical trials
• Target NameNucleoside Antimetabolite/Analog inhibitor
• CAS No. 183204-72-0
• Calculated MW 279.12
• Formulation C9H12Cl2N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.ClC1=C(CN2CCCC2=N)NC(=O)NC1=O
  Pathways:DNA Damage/DNA Repair
  Receptor:Nucleoside Antimetabolite/Analog
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yoshino T, et al. Lancet Oncol. 2012 Oct;13(10):993-1001.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting