• Product NameSKF-86002
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-_alpha_ production in human monocytes (IC50 = 1 _mu_M).
• Target Namep38 MAPK inhibitor
• CAS No. 72873-74-6
• Calculated MW 297.35
• Formulation C16H12FN3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:FC1=CC=C(C=C1)C1=C(N2CCSC2=N1)C1=CC=NC=C1
  Pathways:MAPK
  Receptor:p38 MAPK
  Boling pt:
  Melting pt:
  Solubility:DMSO: >10mM
  Appearance:Yellowish-brown Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Griswold DE, et al. Biochem Pharmacol. 1987 Oct 15;36(20):3463-70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting