• Product NameEdoxaban Tosylate Monohydrate
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityEdoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention
• Target NameFactor Xa inhibitor; Thrombin inhibitor
• CAS No. 1229194-11-9
• Calculated MW 738.27
• Formulation C31H38ClN7O7S2H2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C.O
  Pathways:Metabolism; Others
  Receptor:Factor Xa; Factor Xa; Thrombin
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mg/mL (135.45 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Furugohri T, et al. J Thromb Haemost. 2008, 6(9), 1542-1549.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting