• Product NameAOB2796
• Brief DescriptionInhibitors
• Purification98.08%
• Biological ActivityAC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
• Target NameProteasome agonist
• CAS No. 916170-19-9
• Calculated MW 518.36
• Formulation C25H20BrN5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C/C(=N\NC(=O)C(C1=NNC(=O)C2=CC=CC=C21)NC(=O)C3=CC=CC=C3)/C4=CC(=CC=C4)Br
  Pathways:Proteases/Proteasome; Ubiquitination
  Receptor:Protease-Activated Receptor 2
  Boling pt:
  Melting pt:
  Solubility:DMSO: >10mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gardell LR, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting