• Product NameLY2835219
• Brief DescriptionInhibitors
• Purification99.43%
• Biological ActivityLY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM, respectively.
• Target NameCDK inhibitor
• CAS No. 1231929-97-7
• Calculated MW 506.59
• Formulation C27H32F2N8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(=N3)C3=CC4=C(N=C(C)N4C(C)C)C(F)=C3)C=C2)CC1
  Pathways:Cell Cycle/Checkpoint
  Receptor:CDK4; CDK6
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Patrick J. Roberts, et al. JNCI J Natl Y Inst (2012) 104 (6): 476-487.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting