• Product NamePirfenidone
• Brief DescriptionInhibitors
• Purification99.90%
• Biological ActivityPirfenidone is an inhibitor for?TGF-β?production and TGF-β stimulated collagen production, reduces production of?TNF-α?and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Phase 3.
• Target NameTGF-beta/Smad inhibitor
• CAS No. 53179-13-8
• Calculated MW 185.22
• Formulation C12H11NO
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC1=CN(C(=O)C=C1)C1=CC=CC=C1
  Pathways:Stem Cells
  Receptor:TGFβ2
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 37 mg/mL (199.76 mM); DMSO: 37 mg/mL (199.76 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nakazato H, et al. Eur J Pharmacol, 2002, 446(1-3), 177-185.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting