• Product NameTopiroxostat
• Brief DescriptionInhibitors
• Purification98.95%
• Biological ActivityTopiroxostat(FYX-051) is a novel and potent xanthine oxidoreductase (XOR) inhibitor with IC50 value of 5.3 nM.
• Target NameROS inhibitor
• CAS No. 577778-58-6
• Calculated MW 248.24
• Formulation C13H8N6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:N#CC1=NC=CC(=C1)C1=NNC(=N1)C1=CC=NC=C1
  Pathways:Immunology/Inflammation
  Receptor:XO
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sato T, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting