• Product NameBortezomib (PS-341)
• Brief DescriptionInhibitors
• Purification99.59%
• Biological ActivityBortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM in a cell-free assay.
• Target NameProteasome inhibitor
• CAS No. 179324-69-7
• Calculated MW 384.24
• Formulation C19H25BN4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
  Pathways:Proteases/Proteasome; Ubiquitination
  Receptor:20S proteasome
  Boling pt:
  Melting pt:
  Solubility:DMSO: 76 mg/mL (197.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Adams J, et al. Y Res, 1999, 59(11), 2615-2622.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting