• Product NameAlogliptin Benzoate
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityAlogliptin Benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
• Target NameDPP-4 inhibitor
• CAS No. 850649-62-6
• Calculated MW 461.51
• Formulation C25H27N5O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N.C1=CC=C(C=C1)C(=O)O
  Pathways:Proteases/Proteasome
  Receptor:DPP-4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 200 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Feng J, et al. J Med Chem, 2007, 50(10), 2297-2300.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting