• Product NameCinacalcet hydrochloride
• Brief DescriptionInhibitors
• Purification99.90%
• Biological ActivityCinacalcet hydrochloride (AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism.
• Target NameCaSR activator
• CAS No. 364782-34-3
• Calculated MW 393.87
• Formulation C22H23ClF3N
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:C[C@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
  Pathways:GPCR/G Protein
  Receptor:CaSR
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 33 mg/mL (83.78 mM); DMSO: 79 mg/mL (200.57 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Quarles LD, et al. J Am Soc Nephrol. 2003 Mar;14(3):575-83.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting