• Product NameSKLB1002
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivitySKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.
• Target NameVEGFR inhibitor
• CAS No. 1225451-84-2
• Calculated MW 320.39
• Formulation C13H12N4O2S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C(OC)C=C2C(SC3=NN=C(C)S3)=NC=NC2=C1
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:VEGFR2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 7 mg/mL (21.84 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang S, et al. Clin Y Res. 2011, 17(13), 4439-4450.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting