• Product NamePNU 282987
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityPNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 60 μM).
• Target NameAChR agonist
• CAS No. 123464-89-1
• Calculated MW 301.21
• Formulation C14H18Cl2N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C1CN2CCC1[C@H](C2)NC(=O)C3=CC=C(C=C3)Cl
  Pathways:Neuroscience
  Receptor:α7 nAChR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bodnar AL, et al. J Med Chem. 2005 Feb 24;48(4):905-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting