• Product NameP22077
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityP22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
• Target NameDUB inhibitor
• CAS No. 1247819-59-5
• Calculated MW 315.32
• Formulation C12H7F2NO3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(=O)C1=CC(=C(SC2=C(F)C=C(F)C=C2)S1)[N+]([O-])=O
  Pathways:Ubiquitination
  Receptor:USP2; USP4; USP47; USP5; USP7
  Boling pt:
  Melting pt:
  Solubility:DMSO: 63 mg/mL (199.79 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting