• Product NameEHop-016
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityEHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-435 and MDA-MB-231 cells, equally potent inhibition for Rac3.
• Target NameRho inhibitor
• CAS No. 1380432-32-5
• Calculated MW 430.55
• Formulation C25H30N6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCN1C2=CC=CC=C2C2=C1C=CC(NC1=NC(NCCCN3CCOCC3)=NC=C1)=C2
  Pathways:Cell Cycle/Checkpoint
  Receptor:Rac1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 86 mg/mL (199.74 mM)
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Montalvo-Ortiz BL, et al. J Biol Chem. 2012, 287(16), 13228-13238.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting