• Product NameTG6-10-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTG6-10-1 is an EP2 antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors.
• Target Name5-HT Receptor antagonist
• CAS No. 1415716-58-3
• Calculated MW 448.43
• Formulation C23H23F3N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)NCCN2C3=CC=CC=C3C=C2C(F)(F)F
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2B
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jiang J, et al. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3591-3596.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting