• Product NameNU7026
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityNU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.
• Target NameATM/ATR inhibitor; DNA-PK inhibitor; PI3K inhibitor
• CAS No. 154447-35-5
• Calculated MW 281.31
• Formulation C17H15NO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O=C1C=C(OC2=C1C=CC1=CC=CC=C21)N1CCOCC1
  Pathways:DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
  Receptor:ATM; ATR; DNA-PK; PI3K
  Boling pt:
  Melting pt:
  Solubility:DMSO: 1 mg/mL (3.55 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Veuger SJ, et al. Y Res, 2003, 63(18), 6008-6015.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting