• Product NameKNK437
• Brief DescriptionInhibitors
• Purification97.00%
• Biological ActivityNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40.
• Target NameHSP inhibitor
• CAS No. 218924-25-5
• Calculated MW 245.23
• Formulation C13H11NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C\1CN(C(=O)/C1=C/C2=CC3=C(C=C2)OCO3)C=O
  Pathways:Cytoskeletal Signaling; Metabolism
  Receptor:HSP105; HSP40; HSP72
  Boling pt:
  Melting pt:
  Solubility:DMSO: 15 mg/mL warmed (61.16 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yokota S, et al. Y Res. 2000, 60(11), 2942-2948.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting