• Product NameBAM7
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.
• Target NameBCL inhibitor
• CAS No. 331244-89-4
• Calculated MW 405.47
• Formulation C21H19N5O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCOC1=CC=CC=C1N/N=C/2\C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C
  Pathways:Apoptosis
  Receptor:Bax
  Boling pt:
  Melting pt:
  Solubility:DMSO: 2 mg/mL (4.93 mM)
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gavathiotis E, et al. Nat Chem Biol, 2012, 8(7), 639-645.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting