• Product NameLAQ824 (Dacinostat)
• Brief DescriptionInhibitors
• Purification99.77%
• Biological ActivityLAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is known to activate the p21 promoter.
• Target NameHDAC inhibitor
• CAS No. 404951-53-7
• Calculated MW 379.46
• Formulation C22H25N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)/C=C/C(=O)NO
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC
  Boling pt:
  Melting pt:
  Solubility:DMSO: 76 mg/mL (200.28 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Atadja P, et al. Y Res, 2004, 64(2), 689-695.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting