• Product NameIRAK-1/4 Inhibitor
• Brief DescriptionInhibitors
• Purification99.89%
• Biological ActivityIRAK-1-4 Inhibitor I is an inhibitor of both IRAK-1 and IRAK-4 with IC50 values of 0.3μM and 0.2μM , respectively
• Target NameAntiviral inhibitor
• CAS No. 509093-47-4
• Calculated MW 395.41
• Formulation C20H21N5O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:[O-][N+](=O)C1=CC=CC(=C1)C(=O)NC1=NC2=CC=CC=C2N1CCN1CCOCC1
  Pathways:Immunology/Inflammation
  Receptor:IRAK-1; IRAK-4
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Powers JP, et al. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting