• Product NamePIK-90
• Brief DescriptionInhibitors
• Purification98.25%
• Biological ActivityPIK-90 is a PI3Kα/γ/δ inhibitor with IC50 of 11 nM/18 nM/58 nM, respectively, less potent to PI3Kβ(IC50= 350 nM).
• Target NamePI3K inhibitor
• CAS No. 677338-12-4
• Calculated MW 351.36
• Formulation C18H17N5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=C(OC)C2=C(C=C1)C1=NCCN1C(NC(=O)C1=CN=CC=C1)=N2
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 0.28 mg/mL (0.79 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Van Keymeulen A, et al. J Cell Biol. 2006, 174(3), 437-445.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting