• Product NameA 769662
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM in cell-free assays, little effect on GPPase/FBPase activity.
• Target NameAMPK activator; Fatty Acid Synthase inhibitor
• CAS No. 844499-71-4
• Calculated MW 360.39
• Formulation C20H12N2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC1=CC=CC=C1C1=CC=C(C=C1)C1=CSC2=C1C(O)=C(C#N)C(=O)N2
  Pathways:Metabolism; PI3K/Akt/mTOR signaling
  Receptor:AMPK; FAS
  Boling pt:
  Melting pt:
  Solubility:DMSO: 72 mg/mL (199.78 mM)
  Appearance:Deep Brownness Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pevton KJ, et al, J Pharmacol Exp Ther, 2012, Jun 13.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting