• Product NameUNBS-5162
• Brief DescriptionInhibitors
• Purification98.37%
• Biological ActivityUNBS5162 is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate Ys; the mean antiproliferative activity IC50 value is 17.9 uM for 9 Y cell lines; hydrolysis product of UNBS3157.
• Target NameCXCR antagonist
• CAS No. 956590-23-1
• Calculated MW 326.35
• Formulation C17H18N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN(C)CCN1C(=O)C2=CC=CC3=CC(NC(N)=O)=CC(C1=O)=C23
  Pathways:Autophagy; GPCR/G Protein; Immunology/Inflammation
  Receptor:CXCL
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Mijatovic T, et al. Neoplasia. 2008 Jun;10(6):573-86.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting