• Product NameAscomycin (FK520)
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityAscomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.
• Target Namephosphatase inhibitor
• CAS No. 104987-12-4
• Calculated MW 792.01
• Formulation C43H69NO12
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C
  Pathways:Others
  Receptor:calcineurin phosphatase
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (126.26 mM); DMSO: 100 mg/mL (126.26 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hatanaka H, et al. J Antibiot (Tokyo). 1988, 41(11), 1592-1601.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting