- Product NameBaricitinib (LY3009104, INCB028050)
- Brief DescriptionInhibitors
- Purification99.50%
- Biological ActivityBaricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
- Target NameChk inhibitor; JAK inhibitor; Tyrosine Kinases inhibitor
- CAS No. 1187594-09-7
- Calculated MW 371.42
- Formulation C16H17N7O2S
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;
