• Product NameCerdulatinib
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.
• Target NameJAK inhibitor; Syk inhibitor
• CAS No. 1198300-79-6
• Calculated MW 445.54
• Formulation C20H27N7O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCS(=O)(=O)N1CCN(CC1)C1=CC=C(NC2=NC=C(C(N)=O)C(NC3CC3)=N2)C=C1
  Pathways:Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
  Receptor:JAK1; JAKs; Syk
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Coffey G, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):538-48.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting