• Product NameBAY 87-2243
• Brief DescriptionInhibitors
• Purification99.77%
• Biological ActivityBAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor. Phase 1.
• Target NameHIF inhibitor
• CAS No. 1227158-85-1
• Calculated MW 525.53
• Formulation C26H26F3N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC1=CC(=NN1CC1=CC(=NC=C1)N1CCN(CC1)C1CC1)C1=NC(=NO1)C1=CC=C(OC(F)(F)F)C=C1
  Pathways:Angiogenesis; Chromatin/Epigenetic
  Receptor:HIF-1α
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 8 mg/mL warmed (15.22 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ellinghaus P, et al. Y Med. 2013, 2(5), 611-624.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting