• Product NamePD 151746
• Brief DescriptionInhibitors
• Purification98.23%
• Biological ActivityPD 151746 is a selective, cell-permeable calpain inhibitor with Ki of 0.26 μM for μ-Calpain, about 20-fold selectivity over m-calpain.
• Target NameCysteine Protease inhibitor
• CAS No. 179461-52-0
• Calculated MW 237.25
• Formulation C11H8FNO2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C1=CC2=C(C=C1F)C(=CN2)/C=C(/C(=O)O)\S
  Pathways:Proteases/Proteasome
  Receptor:m-calpain; μ-Calpain
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 47 mg/mL (198.1 mM); DMSO: 47 mg/mL (198.1 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang KK, et al. Proc Natl Acad Sci U S A. 1996, 93(13), 6687-6692.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting