• Product NameLomeguatrib
• Brief DescriptionInhibitors
• Purification99.39%
• Biological ActivityLomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM.
• Target NameDNA Alkylation inhibitor
• CAS No. 192441-08-0
• Calculated MW 326.17
• Formulation C10H8BrN5OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:NC1=NC2=C(NC=N2)C(OCC2=CC(Br)=CS2)=N1
  Pathways:DNA Damage/DNA Repair
  Receptor:O6-alkylguanine-DNA-alkyltransferas
  Boling pt:
  Melting pt:
  Solubility:DMSO: 65 mg/mL (199.28 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. McElhinney RS, et al. J Med Chem, 1998, 41(26), 5265-5271.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting