• Product NamePritelivir (BAY 57-1293)
• Brief DescriptionInhibitors
• Purification98.70%
• Biological ActivityPritelivir (BAY 57-1293) is a potent helicase primase inhibitor, exhibiting antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2.
• Target NameDNA/RNA Synthesis antagonist
• CAS No. 348086-71-5
• Calculated MW 402.49
• Formulation C18H18N4O3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN(C(=O)CC1=CC=C(C=C1)C1=CC=CC=N1)C1=NC(C)=C(S1)S(N)(=O)=O
  Pathways:DNA Damage/DNA Repair
  Receptor:helicase primase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 80 mg/mL (198.76 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kleymann G, et al. Nat Med. 2002, 8(4), 392-398.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting