• Product NameDesloratadine
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityDesloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
• Target NameHistamine Receptor antagonist
• CAS No. 100643-71-8
• Calculated MW 310.82
• Formulation C19H19ClN2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:
  Melting pt:150-151C
  Solubility:Ethanol: 62 mg/mL (199.47 mM); DMSO: 26 mg/mL (83.64 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Geha RS, et al. J Allergy Clin Immunol, 2001, 107(4), 751-762.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting