• Product NameAlcaftadine
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAlcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
• Target NameHistamine Receptor antagonist
• CAS No. 147084-10-4
• Calculated MW 307.39
• Formulation C19H21N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1CCC(CC1)=C1C2=NC=C(C=O)N2CCC2=CC=CC=C12
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor; H2 receptor; H4 receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40mg/mL
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Namdar R and C Valdez Alcaftadine. Drugs Today (Barc), 2011. 47(12): p. 883-90.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting